Should I take Meloxicam at night or in the morning?

Should I take Meloxicam at night or in the morning?
Written by Medhaavi Mishra

There are some recent studies on if meloxicam should be taken either at night or in the morning. The ideal time when you should take Meloxicam is in the afternoon. When compared to taking it at night, it might function better and cause fewer side effects. This may be influenced by our circadian rhythm, which peaks during the day (active time). There is a greater likelihood that s-o meloxicam will be effective.

In the evening, you might be at risk for negative consequences. Meloxicam is a strong NSAID that must be prescribed by a physician. If you experience any severe side effects or an allergic reaction, speak with your doctor right away. Meloxicam is a well-known non-steroidal anti-inflammatory medication (NSAID). Patients with rheumatoid arthritis, juvenile idiopathic arthritis, or osteoarthritis in children 2 years of age should take it. Along with it, older are frequently prescribed this medication. Due to its ability to help patients with pain, swelling, joint pain, and fever reduction, it is prescribed by doctors as an NSAID.

You should take this medication, which is offered to patients in a variety of dosage forms by your doctor. Some patients feel that taking the medication during the day rather than at night has a positive effect. This is even though the initial dose and form are advised. Meloxicam has side effects if it is not taken as directed. If given the choice between day and night, this NSAID performs better when acquired in the morning. This article will go into more detail.

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What is Meloxicam?

Meloxicam is a non-steroidal anti-inflammatory medication (NSAID). It is a drug used to treat arthritis-related conditions. The drug is used to treat symptoms like swelling, pain, and joint stiffness. This medicine helps stop the body from making proteins that cause pain and swelling. The powerful painkiller meloxicam, which requires a prescription from a doctor, comes in several dosage forms, including,

  1. Standard tablet
  2. Capsule
  3. Oral liquid suspension
  4. Disintegrating tablet

You should consult your doctor before taking meloxicam. If you have a chronic condition like arthritis, talk to your doctor before starting Meloxicam. Some well-known brands of meloxicam include Mobic, Vivlodex, Qmiiz ODT, and Comfort Pac-Meloxicam. The Mobic brand name refers to the meloxicam tablets produced by Boehringer Ingelheim Pharmaceuticals. Other pharmaceutical firms like Apotex and Lupin Pharmaceuticals frequently manufacture generic Meloxicam.

What are Meloxicam’s medical applications?

Meloxicam is a powerful and effective non-steroidal anti-inflammatory drug (NSAID) that is used to treat various types of arthritis, severe pain, and inflammation. Additionally, it can be prescribed after surgery to reduce pain and swelling. Meloxicam can regulate the body’s release of chemicals that could otherwise result in pain, fever, and inflammation. 

The following clinical circumstances can benefit from meloxicam treatment:

  • Rheumatoid arthritis 
  • Osteoarthritis 
  • Juvenile rheumatoid arthritis

Let us discuss one one by one-by-one:

The rheumatoid arthritis

The painful condition known as rheumatoid arthritis causes inflammation and excruciating pain in various joints throughout the body. It is an autoimmune disorder that could be fatal. It has been said by some to be a condition that can make it difficult for you to carry out even the most fundamental activities, like eating, sleeping, or carrying out other tasks. A permanent disability could occur if the illness worsens over time and is not carefully managed.

Meloxicam has had success treating the pain and inflammation brought on by rheumatoid arthritis. Several researchers investigated Meloxicam’s safety and efficiency in treating RA. They also discovered that the drug produced observable differences from the clinical trial’s placebo.

  • Recommended dosages:

Adults: The initial dosage of the medication should be 7.5 mg, given once daily. The doctor may later raise the dose based on how serious the condition is. However, the daily dosage should not exceed 15 mg.

The Osteoarthritis

Osteoarthritis is probably the most common type of arthritis worldwide. Because osteoarthritis can result from the body’s hormonal changes. Women are more affected than men, and those who have just gone through menopause are more susceptible. This condition can affect the finger, hip, or knee joints. If it is not properly managed and treated, it can also become extremely painful and lead to disability.

Meloxicam has also been authorized for the treatment of osteoarthritis pain and inflammation. However, because it is a strong NSAID, it should only be used when directed by a doctor.

  • Recommended dosages

Adults: The initial treatment dose is 7.5 mg, given once daily. The doctor may later raise the dose based on how serious the condition is. However, the daily dosage should not exceed 15 mg.

Children: Depending on the patient’s weight and the severity of their condition, the healthcare provider will decide on the dosage.

The Juvenile rheumatoid arthritis

Juvenile rheumatoid arthritis is the term used to describe rheumatoid arthritis in children who are 16 years of age or younger. The condition has the same complications as rheumatoid arthritis and causes excruciating pain, inflammation, and fever. It can affect kids as young as 6 years old. Meloxicam can be used to treat the signs of juvenile rheumatoid arthritis. Because it can be given to kids older than 2 years old.

But never give Meloxicam to a young child without a doctor’s prescription. Based on the child’s condition and weight, the healthcare professional should choose the appropriate dosage and frequency.

  • Recommended dosages

Young children who are two years old: The right dosage is decided by the doctor. The initial dosage is 0.125 mg for every kilogram of body weight. Later, the doctor might adjust the dosage. But the daily maximum shouldn’t exceed 7.5 mg.

Children under 2 years old: The appropriate dose is decided by the healthcare provider based on the condition’s severity and the child’s weight.

How does it work?

Meloxicam is a medication that can be used to treat a range of diseases, surgeries, and wounds. It causes inflammation and pain. Meloxicam works by preventing the enzymes cyclooxygenase (COX)-1 and COX-2 from doing their job. It stops the production of prostaglandins. Prostaglandins increase body temperature and facilitate the transmission of pain through nerve endings.

Meloxicam is a member of the class of drugs known as NSAIDs (nonsteroidal anti-inflammatory medications).


  1. Effective in treating pain and inflammation associated with rheumatoid arthritis and osteoarthritis.
  2. Should receive treatment for headaches, menstrual cramps, and colds. Additionally, it can be used to treat flu-like symptoms.
  3. NSAIDs (including meloxicam) are regarded as the first line of treatment for moderate to mild arthritis, provided that the correct dosages are taken. are inexpensive, secure, and easily accessible. Additionally, they don’t cause dependence.
  4. Reduces inflammation and pain.
  5. Some of them can be combined with other medications, while others can be purchased as single medications.
  6. Whether food is consumed with it or without it.
  7. Oral tablets, capsules, and suspensions are easily accessible. The bioavailability of tablets and suspension is the same. It is advised to use the suspension because it is simpler to determine the dosage for kids who weigh less than 60 kg.
  8. No dosage adjustment is required for mild to moderate renal or hepatic impairment. It has not been studied in patients with severe liver or kidney disease.
  9. Today, generic meloxicam is accessible.


If you are between the ages of 18 and 60 and are not currently taking any other prescription medications. And also, if you do not have any other medical conditions, you might experience the following side effects:
  1. Gastrointestinal side effects like bleeding, indigestion, and heartburn. Bleeding, nausea, vomiting, constipation, diarrhea, or nausea are additional potential symptoms. Patients are more likely to experience side effects. Side effects include stomach-related ones, if they are elderly, and taking other medications that affect the stomach. Or if they drink more than three glasses of alcohol per day. Meloxicam is thought to have a lower risk of stomach-related side effects when compared to other NSAIDs.
  2. There is evidence that using many NSAIDs may increase your risk of having a heart attack or stroke. They may be at greater risk from higher doses and people who already have cardiovascular problems. The use of NSAIDs can cause high blood pressure, and increase the risk of developing it.
  3. Some people might not be good candidates for it, including those with kidney disease, stomach ulcers, other digestive problems, pre-existing cardiovascular diseases, or a history of repeated heart attacks. It shouldn’t be given to sick people or those who recently had a coronary bypass graft.
  4. NSAIDs, such as meloxicam, should not be used during the last three months of pregnancy. Because they may cause an early collapse of the embryonic arteriosus ductus. The developing kidneys of the fetus can also be harmed by taking NSAIDs after 20 weeks of pregnancy. This can lead to oligohydramnios (low amniotic fluid volume) and, in rare cases, kidney damage. When NSAID treatment is recommended for a period of 20 to 30 weeks, choose the dosages that are most effective for the shortest amount of time. NSAID use is not advised after 30 weeks of pregnancy.

Should I take Meloxicam at night or in the morning?

Only available by prescription, meloxicam is typically taken every day. It makes no difference how you consume meloxicam or whether your doctor has given you a prescription. To achieve stable levels, this medication must be taken at the same time each day. There isn’t a specific time for taking medication; you can do it whenever your doctor instructs you to, day or night. It is suggested that you take this medication with a single 8-ounce (240 milliliters) glass of water for best results. To prevent stomach upset, drink a cup of milk or eat a small snack before taking the meloxicam medication.

How much meloxicam should be taken every day?

Meloxicam is thought to be a more potent and effective analgesic. Follow the doctor’s instructions for taking the meloxicam medication exactly. Only 15 mg of Meloxicam should be taken by adults at once. Patients with kidney issues should speak with or consult their doctor before taking this medication. They might only require a smaller dosage on average.

For kids weighing at least 60 kg, the maximum daily dose of oral Meloxicam is 7.5 mg (132 lbs). Higher doses of Meloxicam have no additional advantages for children. Never forget that meloxicam tablets should not be given to children who weigh less than 60 kg (132 lbs).

How is Meloxicam to be administered?

Meloxicam should be taken cautiously to get the best temperature response from it. As we’ve already discussed, you can take it as often as you like, but you must make sure to only take it once daily at the same time. Meloxicam comes in two dosage forms:

  • Meloxicam tablets
  • Meloxicam oral liquid suspension

You can eat it with or without food. Meloxicam may cause heartburn because it is an NSAID, which causes your stomach’s acidity to rise. Take the medication with food, ideally in between meals, if it causes you that much discomfort. Eating will protect your stomach from being attacked by too much acid in this way. Don’t take the medication more than once a day, please. Contact your doctor as soon as you can in the event of an unintentional overdose. And ensure to properly inform them of the medication’s dosage and timing. Moreover, keep animals and kids away from the bottle.

What dangers come with taking Meloxicam?

Meloxicam comes with some warnings and is not a good drug option for everyone. Meloxicam is not advised for use in cardiac patients. Because it increases the risk of having a heart attack. Ensure to check with your doctor if you have a cardiac condition before using Meloxicam on your own. It is best to stay away from meloxicam if you recently had a heart attack. Patients with irritable bowel syndrome (IBS), gastric or duodenal ulcers, or any other gastrointestinal condition should also avoid using it.

Meloxicam has the potential to exacerbate stomach acidity and gastrointestinal mucosa damage. Additionally, stomach bleeding could happen. Be sure to properly inform your doctor if you’re taking any other medications in addition to Meloxicam, especially any of the following:

  • Blood thinners or anticoagulants like warfarin, clopidogrel, etc.
  • Non-steroidal anti-inflammatory drugs in addition (NSAIDs)
  • Antidepressants include Fluoxetine, Paroxetine, Sertraline, Escitalopram, Venlafaxine, Imipramine, Amitriptyline, etc.
  • Steroid-containing drugs
  • Antipsychotics
  • Antihypertensives

Drug interactions should be considered before taking any medication with another. This is why it’s so important to provide your GP with all the information they require regarding your medical history.

Considerations for taking meloxicam

Depending on the condition you have, your doctor will recommend meloxicam tablets or capsules. The amount of pain will also affect the dosage that is advised. Meloxicam’s drawback is that it must constantly be present in your body in some quantity for it to work as intended. Numerous cautions and warnings have been issued regarding a specific medication. Due to the severe side effects, it is impossible to take too much or too little of this medication.

You must take the medication as directed by your doctor, both when and how much. Inform your doctor of your medical history as well as any additional illnesses you may be experiencing.

This will make it easier for your doctor to select the ideal dosage. Additionally, meloxicam can interact with a variety of other drugs and have several harmful side effects. Harmful effects include nausea and excruciating stomach pain. If you forget to take a dose, do so as soon as you remember. If the time for the next dose is drawing near, skip it. Quickly move on to the next step. If you take two dosages at once to finish the prescription, you run the risk of suffering a severe adverse effect or allergic reaction.

Does daily meloxicam use pose a risk?

15 mg of meloxicam can be taken once daily, ideally in the morning. Meloxicam is prescribed to people who have rheumatoid arthritis, osteoarthritis, or severe pain brought on by any internally inflammatory disease. It is available as a tablet and must only be used at the discretion of a licensed practitioner. An individual with arthritis experiences a great deal of pain and discomfort. They must employ pain-relieving strategies. They want to take painkillers, like Meloxicam, as frequently as they can each day.

Warnings for meloxicam

More than any other OTC NSAID, meloxicam has a broad impact on how your body functions. Therefore, it is preferable to take some precautions before using the medication.

Liver problems

The likelihood of liver issues increases with this medication use. If you or your child displays several symptoms, such as those listed below, seek medical attention right away. Abdominal ache or pain, diarrhea, dark urine, nausea, vomiting, itching, nausea, and vomiting; skin rashes; swelling of the feet or lower legs; unusual fatigue; or yellow eyes or skin.

Allergy symptoms

Anaphylaxis, a potentially fatal allergic reaction, has been linked to meloxicam. Regardless of how uncommon it might be, aspirin or other NSAID allergy sufferers may frequently experience this side effect. To avoid death, anaphylaxis is a serious condition that requires immediate medical attention.


If this medication is taken later in the pregnancy, the unborn child is at risk. While taking the medication, call your doctor as soon as you notice anything that might be a sign of pregnancy. This medication has the potential to decrease sperm count in men. And also, to postpone ovulation in women, which may affect a couple’s ability to conceive. Please consult your doctor before using this medication if you are pregnant or plan to become pregnant. Call your doctor right away if you experience any unexpected side effects while taking this medication, such as edema or weight gain.

Vascular issues

There may be a higher risk of stroke, blood clots, and cardiovascular disease when taking this medication. Users of this medication for an extended period who already have heart or blood vessel problems are more vulnerable. If you experience any of the following, you should contact your doctor right away: chest pain or discomfort, nausea or vomiting, pain in the arms, jaw, back, or neck, difficulty breathing, slurred speech, or weakness.


If taken in high doses, meloxicam may have undesirable side effects like groin bleeding and stomach ulcers. The risk of a heart attack, stroke, or blood clots can also increase. Negative side effects are also possible for people who have had a heart attack or blood vessel disease. Especially if you take the medication frequently. It can cause body aches, arm aches, leg aches, nausea, irritability, mouth sores, neck aches, slurred speech, and weakness. If you are younger than 60 or a child, it is best to consult your doctor once taking Meloxicam or any other medications.

About the author

Medhaavi Mishra